WebFeb 26, 2010 · By the late 1970s, the idea that mature, bloodstream neutrophils were terminally differentiated, end-of-line cells was being questioned. In a series of … WebJul 9, 2010 · The histotoxic potential of neutrophils dictates the need for effective processes to prevent inappropriate tissue-specific accumulation and activation. The key mechanism for this is priming, which dictates that neutrophil activation is a two-step process that requires an initial exposure to mediators such as cytokines.
Mechanical deformation induces depolarization of neutrophils
WebAug 1, 2004 · In vivo priming of neutrophils through peritoneal elicitation is likely to be a stronger stimulus for cell priming than in vitro treatment with cytokines. In peritoneal … WebLittle is known about the priming mechanism of oxidative pathways in neutrophils of people with diabetes. In this study, the kinetics of p47 phox activation was investigated by comparing neutrophils from diabetic and healthy subjects, and the mechanism of hyperglycemia-induced changes was studied by using neutrophil-like HL-60 cells as a … start snipping tool with print screen key
Priming of the neutrophil NADPH oxidase activation: role of …
WebMechanical perturbations, such as shear stresses and cell stretching, can also induce activation of quiescent neutrophils, just like biochemical agents (9, 10).Furthermore, … WebNeutrophils play an important role in immune complex (IC)-mediated diseases, but the mechanisms underlying their recruitment to sites of IC deposition remain largely … WebJun 14, 2016 · GM-CSF pretreatment greatly increased p38 MAPK phosphorylation and promoted CD11b/CD66b expression in human neutrophils treated with mitochondrial and, … pet gear short bi fold carpeted pet ramp