Phospho-sting-s365
WebOct 24, 2013 · We conclude that phosphorylation of S366 (S365 in murine STING) occurs after autophagy and may negatively regulate STING activity to prevent sustained type I IFN production following activation by cytosolic dsDNA. ... 39-2700, used for murine IRF3); anti-IRF3 (Santa Cruz Biotechnology, sc-9082); anti-phospho-IRF3 (Cell Signaling, 4947); anti ... WebStimulator of interferon genes (STING, TMEM173, MITA) is a transmembrane adaptor protein that is a critical component of the cellular innate immune response to pathogenic cytoplasmic DNA (1,2). STING is a …
Phospho-sting-s365
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WebJul 7, 2024 · Phospho-S365 acts as a docking site for IRF3, a transcription factor that is phosphorylated and activated by TBK1, leading to transcriptional induction of type I … WebJun 25, 2024 · In infected cells, STING is phosphorylated on S366 (S365 in mouse) and is K63 linked ubiquitinated, confirming the presence of its activated form at later time points following RNA virus infection, similarly to what has been observed by others after infection with DNA virus ( Chiang and Gack, 2024 ). Results
WebWhole cell lysates were analyzed by WB for phospho-STING (p-STING S365), STING, phospho-TBK1 (p-TBK1 S172), TBK1, phospho-IRF3 (p-IRF3 S396), IRF3, IFIT1, cGAS and FLAG (for disA expression). β-actin levels were used as loading control. Data are representative of three independent experiments. WebPhospho-STING (Ser366) Antibody recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein.
WebAnti-STING Antibody from Assay Genie is a high quality, highly sensitive antibody with reactivity against Human, Mouse, Rat and validated in WB IHC. ... Phospho-STING-S365 Rabbit pAbProduct Code:CABP1199Size:20uL, 50uL, 100uLSynonyms:ERIS, MPYS, Mita, STING, Tmem173, CABP1199 WebAnti-Phospho-STING-S365 antibody produced in rabbit. View Price and Availability. Sigma-Aldrich. ABF124. Anti-cGAS Antibody. from rabbit, purified by affinity chromatography. View Price and Availability. Sigma-Aldrich. D7290. Deoxyribonucleic acid from herring sperm. single-stranded for hybridization.
WebPhospho-STING-S365 Rabbit pAb: Product Code: CABP1199: Size: 20uL, 50uL, 100uL: Synonyms: ERIS, MPYS, Mita, STING, Tmem173, STING-beta, 2610307O08Rik: …
WebJun 3, 2024 · In clones in which VPS13C protein expression had been successfully restored, phospho-STING and phospho-TBK1 were restored to WT ... cat# 19781, … how to stop hooded eyelidsWebJul 7, 2024 · To initiate signaling, serine 365 (S365) in the C-terminal tail (CTT) of STING is phosphorylated, leading to induction of type I interferons (IFNs). Additionally, evolutionary conserved... read alchemy books onlineWeb靶标信息. STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF … how to stop hoover smellingWebSTING is a four transmembrane (a.a. 21-41, 47-67, 87-106, 116-136) protein with both its N- and C-terminal ends exposed intracellularly (a.a. 1-20 and 137-379).The C-terminal cytoplasmic tail contains the c-di-GMP-binding domain (CBD; a.a. 153-340) with two c-di-GMP-binding regions (a.a. 162-167 & 238-241). Spécificité how to stop hooking golf ballWebMouse Phospho-STING (Ser365) control lysateHTRF® This lysate is a component of the Mouse Phospho-STING (Ser365) kit. It may be used as a residue specific positive control … read alexa riley books online freeWebSTING is a four transmembrane (a.a. 21-41, 47-67, 87-106, 116-136) protein with both its N- and C-terminal ends exposed intracellularly (a.a. 1-20 and 137-379).The C-terminal cytoplasmic tail contains the c-di-GMP-binding domain (CBD; a.a. 153-340) with two c-di-GMP-binding regions (a.a. 162-167 & 238-241). 特異性 how to stop hooveringWeb(APR30276N) Phospho-STING-S365 Rabbit pAb (APR30276N) - Leading Biology - CiteAb A rabbit polyclonal antibody, raised against Stimulator of interferon genes protein (Mouse), … read alice in borderland retry